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Transcriptome profiling of PAXX knockdown in HCT116 colorectal cancer cells

ABSTRACT: To investigate the transcriptional changes induced by PAXX depletion in colorectal cancer cells, bulk RNA sequencing was performed in HCT116 cells transfected with PAXX-targeting siRNA or negative-control siRNA. Three independent biological replicates were analyzed for each group.

ORGANISM(S): Homo sapiens

PROVIDER: GSE346887 | GEO | 2026/09/15

REPOSITORIES: GEO

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Transcription changes due to TET1 knockdown in HCT116 colorectal cancer cells.

Project description:Transcriptional profiling of HCT116 cells transfected with either control siRNA or TET1 siRNA was analyzed using whole human genome microarrays. To identify genes regulated by TET1 in colorectal cancer, HCT116 cells were transfected with either control siRNA or TET1 siRNA, and total RNA was extracted from biologically duplicated samples.

2015-09-04 | E-GEOD-66512 | biostudies-arrayexpress

Transcription changes due to TET1 knockdown in HCT116 colorectal cancer cells.

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