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Extravascular and intravascular skin T cells in acute (armstrong) LCMV infection [I50, I51]

ABSTRACT: This study is part of the immgenT Open Source Project, specifically IGT50 and IGT51, which focuses on the characterization of extravascular and intravascular skin T cells during acute lymphocytic choriomeningitis virus (LCMV) Armstrong infection.

ORGANISM(S): Mus musculus

PROVIDER: GSE347939 | GEO | 2026/09/23

REPOSITORIES: GEO

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Splenic T cells in dirty mice in acute LCMV (armstrong) infection [I45]

Project description:This study is part of the immgenT Open Source Project, specifically from IGT45, which focuses on characterizing splenic T cells in "dirty" mice during acute lymphocytic choriomeningitis virus (LCMV, Armstrong strain) infection.

2026-09-23 | GSE347935 | GEO

Extravascular and intravascular skin T cells in acute (armstrong) LCMV infection [I50, I51]

Project description:Extravascular and intravascular skin T cells in acute (armstrong) LCMV infection [I50, I51]

| PRJNA1531651 | ENA

Pan organ and time course analysis of T cells in acute LCMV (armstrong) infection (day 60) [I40]

Project description:This study is part of the immgenT Open Source Project, specifically from IGT40, which focuses on a pan-organ and time course analysis of T cells in acute LCMV (Armstrong) infection at day 60 post-infection. The dataset includes T cells isolated from multiple organs: spleen, prostate, submandibular gland, bone marrow, mesenteric lymph node, small intestine epithelium, small intestine lamina propria, lung, and mediastinal lymph node. 7-week-old male C57BL/6J mice infected intraperitoneally with 2×10^5 PFU LCMV Armstrong, and T cells were analyzed at 60 days post-infection (dpi). The study includes both endogenous T cells and adoptively transferred P14 and SMARTA TCR transgenic T cells. Mice received IV 100,000 SMARTA (CD45.1.2) and 50,000 P14 (CD45.1) T cells one day before infection.

2025-08-19 | GSE301961 | GEO

Pan organ and time course analysis of T cells in acute LCMV (armstrong) infection (day 7) [I36]

Project description:This study is part of the immgenT Open Source Project, specifically from IGT36, which focuses on a pan-organ and time course analysis of T cells in acute LCMV (Armstrong) infection at day 7 post-infection. The dataset includes T cells isolated from multiple organs: spleen, prostate, submandibular gland, bone marrow, mesenteric lymph node, small intestine epithelium, small intestine lamina propria, lung, and mediastinal lymph node. 7-week-old male C57BL/6J mice infected intraperitoneally with 2×10^5 PFU LCMV Armstrong, and T cells were analyzed at 60 days post-infection (dpi). The study includes both endogenous T cells and adoptively transferred P14 and SMARTA TCR transgenic T cells. Mice received IV 100,000 SMARTA (CD45.1.2) and 50,000 P14 (CD45.1) T cells one day before infection.

2025-08-19 | GSE301271 | GEO

Pan organ and time course analysis of T cells in acute LCMV (armstrong) infection (day 30) [I38]

Project description:This study is part of the immgenT Open Source Project, specifically from IGT38, which focuses on a pan-organ and time course analysis of T cells in acute LCMV (Armstrong) infection at day 30 post-infection. The dataset includes T cells isolated from multiple organs: spleen, prostate, submandibular gland, bone marrow, mesenteric lymph node, small intestine epithelium, small intestine lamina propria, lung, and mediastinal lymph node. 7-week-old male C57BL/6J mice infected intraperitoneally with 2×10^5 PFU LCMV Armstrong, and T cells were analyzed at 60 days post-infection (dpi). The study includes both endogenous T cells and adoptively transferred P14 and SMARTA TCR transgenic T cells. Mice received IV 100,000 SMARTA (CD45.1.2) and 50,000 P14 (CD45.1) T cells one day before infection.

2026-03-23 | GSE301960 | GEO

LCMV-Armstrong infection

Project description:LCMV-Armstrong infection

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Gene expression profile analysis of mouse whole spleen following infection by lymphocytic choriomeningitis virus (LCMV), comparing LCMV-Armstrong and LCMV-Clone 13 expression patterns at 0, 5, 9, and 30 days

Project description:To identify mechanisms behind immunosuppression during virus infections, we infected mice with LCMV-Armstrong and LCMV-Clone 13 expression patterns. LCMV-Armstrong induces a T-cell reaction that resolves infection within 8-10 days, while LCMV-Clone13 generates a persisten infection through immunosuppression. We used microarray to uncover splenic gene expression patterns specific to each LCMV infection at 5, 9, and 30 days C57BL6 mice, 6-10 weeks old, were infected with LCMV-Armstrong and LCMV-Clone 13 or left uninfected (naïve). At days 5, 9, and 30 whole spleens were harvested for RNA extraction and hybridization on Affymetric microarray.

2013-02-15 | E-GEOD-44322 | biostudies-arrayexpress

2013-02-15 | GSE44322 | GEO

ERRBS dataWT and TET2cKOgp33+ CD8+ T cells isolated on D8 LCMV-Armstrong infection

Project description:The epigenetic modifier TET2 plays a role in cell fate decisions in hematopeotic stem cells and CD4+ Th1 and Th17 differentiation. Here, we demonstrate that loss of TET2 promotes CD8+ memory differentiation following acute viral infection with LCMV-Armstrong.

2017-10-20 | GSE105176 | GEO

Areas of H3K27 tri-methylation in CD8+ T cells from the spleens of LCMV-Armstrong or LCMV-Clone 13 infected mice

Project description:The profiles of H3K27 tri-methylation in CD8+ T cells from LCMV-Armstrong and LCMV-Clone 13 infected mice are known to be distinct from one another. We used CUT&RUN (Cleavage Under Targets and Release Using Nuclease) to analyze these differences in splenic CD8+ T cells of these two infection conditions.

2023-01-04 | GSE213467 | GEO

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