Transcriptomics

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Expression data from three endothelial cell lines derived from murine embryonic stem cells expressing VE-cadherin, N-cadherin or both


ABSTRACT: Endothelial cells (ECs) express two members of the cadherin family, VE- and N-cadherin. While VE-cadherin induces EC homotypic adhesion, N-cadherin function in ECs remains largely unknown. EC-specific inactivation of either VE- or N-cadherin leads to early foetal lethality suggesting that these cadherins play a non-redundant role in vascular development. Goal of this study was to further investigate this hypothesis analyzing both additive and divergent functions of the two cadherins in ECs.

ORGANISM(S): Mus musculus

PROVIDER: GSE34948 | GEO | 2012/01/10

SECONDARY ACCESSION(S): PRJNA150963

REPOSITORIES: GEO

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