Chip-chip from Z138 MCL cell line with SOX11 antibody

ABSTRACT: To determine the role of SOX11 in aggressive lymphoid neoplasm, we first investigated direct target genes of this transcription factor using chromatin immunoprecipitation and DNA microarrays (ChIP-chip) in MCL cell lines. Analysis of the exact location of SOX11 binding elements showed that SOX11 interacts with DNA predominantly in the enhancer regions (in 40% of the enriched regions) and intron segments (in 33% of the enriched regions), suggesting that in these genes SOX11 may interact with the general transcriptional machinery and transcriptional co-regulators.

ORGANISM(S): Homo sapiens

PROVIDER: GSE35021 | GEO | 2015/01/01

SECONDARY ACCESSION(S): PRJNA151159

REPOSITORIES: GEO