Transcriptomic profiling of mouse lung tissue after osmundacetone treatment in bleomycin-induced pulmonary fibrosis

ABSTRACT: To investigate the transcriptional response to osmundacetone (OSMA) in pulmonary fibrosis, lung tissue RNA was sequenced from male C57BL/6J mice in control, bleomycin model, and bleomycin plus high-dose OSMA groups. Four samples were analyzed per group. The study examined disease-associated expression changes and their reversal by OSMA, with particular attention to extracellular matrix remodeling and TGF-beta-related signaling.

ORGANISM(S): Mus musculus

PROVIDER: GSE351289 | GEO | 2026/10/22

REPOSITORIES: GEO