Genomics

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5-aza-2'-cytidine and trichostatin A effect to gene expression of Epstein-Barr virus-transformed human lymphoblastoid cell lines (LCLs).


ABSTRACT: Investigation of 5-aza-2'-cytidine and trichostatin A effect to gene expression of human LCLs. LCLs estabulished from patients with genetic dissease are commonly used for mRNA or protein analysis of disease related genes. However, ofen times the gene of interset is not expressed in LCL. Epigenetic modification could be overcome this problem.

ORGANISM(S): Homo sapiens

PROVIDER: GSE35359 | GEO | 2012/01/27

SECONDARY ACCESSION(S): PRJNA152745

REPOSITORIES: GEO

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