Transcriptomic responses of MCF-7 and HL-60 cells to Dorema aucheri-derived carbon quantum dots

ABSTRACT: This study investigates the transcriptomic responses of two human cancer cell lines, MCF-7 (breast cancer) and HL-60 (promyelocytic leukemia), to carbon quantum dots (CQDs) synthesized using Dorema aucheri Boiss. The study examines changes in gene expression associated with oxidative stress, mitochondrial dysfunction, apoptosis, and related cellular signaling pathways following CQD exposure. The experimental design comprises untreated control and CQD-treated cells, with three biological replicates per condition as described in the manuscript. RNA-sequencing analysis is intended to characterize differential gene expression and identify biological processes and molecular pathways associated with the cellular responses to CQD treatment.

ORGANISM(S): Homo sapiens

PROVIDER: GSE353938 | GEO | 2026/11/10

REPOSITORIES: GEO