Genomics

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Analysis of microRNAs in bovine early embryonic development


ABSTRACT: In animals, the maternal-to-embryonic transition (MET) is an important step occurring in the first days of early development. This important transition involves the degradation of maternal transcripts that have been stocked during oogenesis and used until this transition. Moreover, some precise and specific control mechanisms must govern the adequate synchronization of the MET events to promote embryonic genome activation. These mechanisms are not well understood, but microRNAs could be one of the mechanisms involved. MicroRNAs are short non-coding RNAs involved in a growing number of pathways by their post-transcriptional repression of mRNA translation. Thus, we analyzed microRNA expression during oocyte maturation by comparing GV-oocytes with MII-oocytes in cow.

ORGANISM(S): Gorilla gorilla Lagothrix Bos taurus Mus musculus Rhinopithecus bieti Rattus norvegicus Pan troglodytes Pan paniscus Canis lupus familiaris Saguinus imperator Homo sapiens Symphalangus syndactylus Monodelphis domestica Macaca nemestrina Ovis aries Ateles sp. Cricetulus griseus Sus scrofa Lemur catta Pongo abelii Macaca mulatta

PROVIDER: GSE35567 | GEO | 2012/02/08

SECONDARY ACCESSION(S): PRJNA152215

REPOSITORIES: GEO

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