Liver transcriptome of sexually mature hens in relation to the formation of the egg yolk

ABSTRACT: We used a transcriptomic approach based on the comparison of the expression between the liver of sexually mature hens versus pre-laying pullets to better appreciate which hepatic proteases and antiproteases are specifically expressed in relation to vitellogenesis. Using a 20K chicken oligoarray corresponding to 12 595 different chicken genes, a total of 582 genes were shown to be over-expressed in the liver at sexual maturity of hens (1.2 to 67 fold- difference). Most of the top ten over-expressed genes are known components of egg yolk or of the perivitelline membrane. The combination of different bioinformatic tools reveals 12 proteases and 3 antiproteases amongst the over-expressed genes, including many predicted proteins with yet unknown functions.

ORGANISM(S): Gallus gallus

PROVIDER: GSE35595 | GEO | 2012/04/01

SECONDARY ACCESSION(S): PRJNA152511

REPOSITORIES: GEO