A PGC-1alpha-dependent decrease in mitochondrial oxidative metabolism in muscle of humans with inherited insulin resistance

ABSTRACT: We used microarrays to assess gene expression profiling of 6 patients with a mutation (Arg1174Gln) in the tyrosine kinase domain of the insulin receptor gene (INSR) and 10 matched healthy controls

ORGANISM(S): Homo sapiens

PROVIDER: GSE36297 | GEO | 2014/02/17

SECONDARY ACCESSION(S): PRJNA153035

REPOSITORIES: GEO