Transcriptomics

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Expression data from caudal artery of Notch3WT and Notch3KO mice


ABSTRACT: Notch3 is a transmembrane receptor which is critically important for the structure and myogenic response of distal arteries, particularly cerebral arteries. After activation of the receptor, the intracellular domain translocates in the nucleus to activate target genes transcription. In order to identify Notch3 target genes, we used microarrays to compare gene expression from caudal arteries (Notch3+/+ vs Notch3-/-) and selected down-regulated genes in Notch3-/- arteries.

ORGANISM(S): Mus musculus

PROVIDER: GSE36437 | GEO | 2012/03/31

SECONDARY ACCESSION(S): PRJNA153179

REPOSITORIES: GEO

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