Synergistic effects of TRAIL and taurolidine on soft tissue sarcoma cell lines

ABSTRACT: Microarray analysis revealed differential gene expression patterns of rhabdomyosarcoma (A-204), leiomyosarcoma (SK-LMS-1) and epithelioid cell sarcoma (VA-ES-BJ) cells treated with TRAIL and/or taurolidine. To explore new therapeutic options in the treatment of sarcomas, we tested the antibiotic taurolidine (TRD) on A-204, SK-LMS-1 and VA-ES-BJ carcinoma cell lines alone and in combination with rhTRAIL (TNF related apoptosis-inducing ligand). Gene expression was analysed by RNA microarray.

ORGANISM(S): Homo sapiens

PROVIDER: GSE36572 | GEO | 2013/03/17

SECONDARY ACCESSION(S): PRJNA153731

REPOSITORIES: GEO