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Expression data from primary breast tumors (IJB+OXF)

ABSTRACT: Frozen tissue specimens from primary breast tumors were collected under IRB-approved protocols from 2 medical centers and profiled using Affymetrix U133 series expression microarrays. This cohort comprises of two subcohorts derived from the Institute Jules Bordet (IJB), Brussels (n=41) (2002) and Guys Hospital, London (n=7) (2003). Dr. Christos Sotiriou (Institute Jules Bordet) directed the microarray work in Brussels. A publication describing the generation of these data is not yet available. However, these data can be used alongside other Affymetrix breast tumour data sets to form large meta-cohorts for breast cancer research, as was done in Lasham et. al. J Natl Cancer Inst. 2012 Jan 18;104(2):133-146.

ORGANISM(S): Homo sapiens

PROVIDER: GSE36773 | GEO | 2012/03/31

SECONDARY ACCESSION(S): PRJNA156851

REPOSITORIES: GEO

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Expression data from primary breast tumors (IJB+OXF)

Project description:Frozen tissue specimens from primary breast tumors were collected under IRB-approved protocols from 2 medical centers and profiled using Affymetrix U133 series expression microarrays. This cohort comprises of two subcohorts derived from the Institute Jules Bordet (IJB), Brussels (n=41) (2002) and Guys Hospital, London (n=7) (2003). Dr. Christos Sotiriou (Institute Jules Bordet) directed the microarray work in Brussels. A publication describing the generation of these data is not yet available. However, these data can be used alongside other Affymetrix breast tumour data sets to form large meta-cohorts for breast cancer research, as was done in Lasham et. al. J Natl Cancer Inst. 2012 Jan 18;104(2):133-146. Frozen tumor tissues comprising of >60% tumor cellularity were extracted for total RNA and hybridized on Affymetrix microarrays. Clinical data was requested, but not provided by submitter

2012-03-30 | E-GEOD-36773 | biostudies-arrayexpress

Expression data from primary breast tumors (Auckland)

Project description:Frozen tissue specimens from primary breast tumors were collected and profiled using Affymetrix U133 plus 2 expression microarrays. A publication describing the generation of these data is not yet available. However, these data can be used alongside other Affymetrix breast tumour data sets to form large meta-cohorts for breast cancer research, as was done in Lasham et. al. J Natl Cancer Inst. 2012 Jan 18;104(2):133-146.

2012-03-31 | GSE36771 | GEO

Expression data from primary breast tumors (NUH)

Project description:Frozen tissue specimens from primary breast tumors were collected under approved protocols and profiled using Affymetrix U133 series expression microarrays. This cohort was assembled at the National University Hospital (NUH), Singapore in 2003, and profiled at the Genome Institute of Singapore, Microarray and Expression Genomics Lab. Dr. Lance D. Miller (Wake Forest University School of medicine) directed the profiling work. A publication describing the generation of these data is not yet available. However, these data can be used alongside other Affymetrix breast tumour data sets to form large meta-cohorts for breast cancer research, as was done in Lasham et. al. J Natl Cancer Inst. 2012 Jan 18;104(2):133-146.

2012-03-31 | GSE36772 | GEO

Expression data from primary breast tumors (Auckland)

2012-03-30 | E-GEOD-36771 | biostudies-arrayexpress

Expression data from primary breast tumors (NUH)

2012-03-30 | E-GEOD-36772 | biostudies-arrayexpress

Effect of TUC338 knockdown on gene expression

Project description:The ultraconserved RNA TUC338 is expressed in hepatocellular cancer and can modulate cell proliferation. Details are provided in Braconi et al,Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):786-91. In this analysis, we knocked down TUC338 in HepG2 cells and analyzed gene expression.

2018-02-09 | GSE110259 | GEO

Fasting-Induced FOXO4 Blunts Human CD4+ T Helper Cell Responsiveness

Project description:This fasting and refeeding pilot study was registered in ClinicalTrials.gov with the registration number NCT02719899 and approved by the National Heart and Lung Institute IRB.

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Boosting NAD+ blunts toll-like receptor-4 induced type I interferon in control and systemic lupus erythematosus monocytes

Project description:This is a pilot study to evaluate the effects of NR supplementation on monocytes function, registered in ClinicalTrials.gov with registration number: NCT02812238 and approved by the National Heart and Lung Institute IRB.

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Expression data from of FACS separated acinar and duct cell at day 4 of suspension cultured human pancreatic exocrine cells

Project description:Donor pancreata were obtained from the Beta Cell Bank of the JDRF Centre for Beta Cell Therapy in Diabetes (Brussels, Belgium), from Pancreatic Islet Processing (ECIT center) of Diabetes Research Institute at the IRCCS San Raffaele Scientific Institute (Milan, Italy) and from the DRWF Human Islet Isolation Facility (Oxford, England). Full written consent for use of donor material for research was obtained according to Belgian, Italian and English laws. This project was approved by the Medical Ethical Committee of all institutions. Cells were cultured in 3D suspension culture for four days in Advanced RPMI supplemented with 5% FBS.

2020-07-18 | GSE154629 | GEO

Expression data from day of isolation and day 4 suspension cultured human pancreatic exocrine cells

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