JAK2 Naive and Persitent Murine BaF3 cells infected with MPLW515L

ABSTRACT: Transcriptional profiling of Murine BaF3 cells infected with MPLW515L grown under either normal conditions (Naive) or in 0.8 uM INCB18424 for 4-6 weeks (Persistent). Naive and Persistent cells were then treated with either DMSO (Control) or 0.8 uM INCB18424 for 4 hours. Goal was to determine transcriptional changes conditioned upon sensitivity/resistance of BaF3 MPLW515L mutants to JAK1/2 specific inhibitor.

ORGANISM(S): Mus musculus

PROVIDER: GSE38335 | GEO | 2012/05/31

SECONDARY ACCESSION(S): PRJNA167738

REPOSITORIES: GEO