Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-Seq of eye tissues from A/J, BALB/c, and C57BL/6 background mice

ABSTRACT: We report RNA-Seq experiments of whole eye tissues from A/J, BALB/c, and C57BL/6 background mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE38359 | GEO | 2012/06/08

SECONDARY ACCESSION(S): PRJNA168144

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

RNA-Seq of eye tissues from A/J, BALB/c, and C57BL/6 background mice

Project description:We report RNA-Seq experiments of whole eye tissues from A/J, BALB/c, and C57BL/6 background mice. Examine ocular tissue from 3 different background mice that display varying rates of retinal degeneration.

2012-06-07 | E-GEOD-38359 | biostudies-arrayexpress

RNA-Seq of eye tissues from C57BL/6J background mice at 1.5 h and 9.0 h after light onset

Project description:We report RNA-Seq experiments of whole eye tissues from C57BL/6J background mice at 1.5 h and 9.0 h after light onset to better understand photoreceptor phagocytosis

2013-08-07 | GSE48974 | GEO

RNA-Seq of eye tissues from C57BL/6J background mice at 1.5 h and 9.0 h after light onset

Project description:We report RNA-Seq experiments of whole eye tissues from C57BL/6J background mice at 1.5 h and 9.0 h after light onset to better understand photoreceptor phagocytosis Examine ocular tissue from mice at different time points

2013-08-07 | E-GEOD-48974 | biostudies-arrayexpress

SJL, Balb: Leg and Eye, 10/12 months

Project description:SJL & Balb. Leg and eye; 1 year, 10 months Keywords: time-course

2004-08-02 | GSE1092 | GEO

Expression data from mouse intestine: C57Bl/6 MTHFR+/- vs BALB/c MTHFR+/-

Project description:Previous studies in our laboratory have shown that low folate diet (control diet with 2mg folate/kg, low folate diet with 0.3mg folate/kg) can induce intestinal tumors in BALB/c mice. In addition, we reported that C57Bl/6J mice did not form tumors under the same conditions. We used microarrays to identify the genetic differences between BALB/c and C57Bl/6J mice that promote tumorigenesis in BALB/c mice.

2013-04-09 | GSE34010 | GEO

RNA-Seq of eye tissues from Monkey eye and retina samples

Project description:We report RNA-Seq experiments of eye and retinal tissues from different ocular compartments in the Monkey

2016-09-12 | GSE84929 | GEO

RNA-Seq of eye tissues from Ground Squirrel eye and retina samples

Project description:We report RNA-Seq experiments of eye and retinal tissues from Ground Squirrel (Ictidomys tridecemlineatus)

2016-09-12 | GSE84931 | GEO

RNA-Seq of tissues from Rat eye and retina samples

Project description:We report RNA-Seq experiments of eye and retinal tissues from Rattus Norvegicus

2016-09-12 | GSE84932 | GEO

Single cell RNA-sequencing of pleural cavity macrophages naïve and nematode-infected C57BL/6 and BALB/c mice

Project description:The recent revolution in tissue-resident macrophage biology has resulted largely from murine studies performed in the C57BL/6 strain. Here, we provide a comprehensive analysis of immune cells in the pleural cavity using both C57BL/6 and BALB/c mice. Unlike C57BL/6 mice, naïve tissue-resident Large Cavity Macrophages (LCM) of BALB/c mice failed to fully implement the tissue residency programme. Following infection with a pleural-dwelling nematode these pre-existing differences were accentuated with LCM expansion occurring in C57BL/6 but not BALB/c mice. While infection drove monocyte recruitment in both strains, only in C57BL/6 mice were monocytes able to integrate into the resident pool. Monocyte to macrophage conversion required both T cells and IL-4Rα signalling. Host genetics are therefore a key influence on tissue resident macrophage biology, and during nematode infection Th2 cells control the differentiation pathway of tissue resident macrophages.

2022-09-01 | GSE189031 | GEO

Genetic Background-Dependent Role of Egr1 for Eyelid Development

Project description:EGR1 is an early growth response zinc finger transcription factor with broad actions, including in differentiation, mitogenesis, tumor suppression, and neuronal plasticity. Here we demonstrate that Egr1-/- C57BL/6-background mice have normal eyelid development, but back-crossing to BALB/c background for 4-5 generations resulted in defective eyelid development by embryonic day E15.5, at which time EGR1 was expressed in eyelids of WT mice. Defective eyelid formation correlated with profound ocular anomalies evident by post-natal days 1-4, including severe cryptophthalmos, microphthalmia or anophthalmia, retinal dysplasia, keratitis, corneal neovascularization, cataracts, and calcification. The BALB/c albino phenotype-associated Tyrc tyrosinase mutation appeared to contribute to the phenotype, as crossing the independent Tyrc-2J allele to Egr1-/- C57BL/6 mice also produced ocular abnormalities, albeit less severe than those in Egr1-/- BALB/c mice. Thus, EGR1 in a genetic background-dependent manner plays a critical role in mammalian eyelid development and closure, with subsequent impact on ocular integrity.

2017-07-30 | GSE100690 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data