Gene expression signatures in miR-29c overexpressed gastric cancer cells.

ABSTRACT: To explain the mechanism that miR-29c affects the cell proliferation, we attempted to identify the miR-29c target genes in gastric carcinoma. The expression profiles in MKN45, MKN7 and MKN74 cells transfected with miR-29c oligo or Negative control oligo were obtained from microarray analysis. Then, the genes differentially expressed (Fold change >= 2.0) in miR-29c-transfected cells compared with negative control-transfected ones were identified in each cell lines, respectively. The differentially expressed genes shared among 3 cell lines were identified as the candidates for miR-29c targets.

ORGANISM(S): Homo sapiens

PROVIDER: GSE38581 | GEO | 2013/03/27

SECONDARY ACCESSION(S): PRJNA168160

REPOSITORIES: GEO