Genomics

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Expression data from Amacr knock-out mouse liver


ABSTRACT: Bile acids play multiple roles in vertebrate metabolism by facilitating lipid absorption in the intestine and acting as a signaling molecule in lipid and carbohydrate metabolism. Bile acids are also the main route to excrete excess cholesterol out of the body. Alpha-methyl-Coa racemase (Amacr) is one of the enzymes needed to produce bile acids from cholesterol. The mouse model lacking Amacr can produce only minor (less than 10%) amounts of bile acids, but still they are symptomless in normal laboratory conditions.

ORGANISM(S): Mus musculus

PROVIDER: GSE40085 | GEO | 2015/12/22

SECONDARY ACCESSION(S): PRJNA172865

REPOSITORIES: GEO

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