Transcriptomics

Dataset Information

0

MRNA profiling of glucose-repressed 14-3-3 and hdac yeast mutants


ABSTRACT: Previous results suggest that Bmh might inhibit the activity of the transcription factor Adr1 after binding to Adr1-dependent promoters. In a strain lacking the two major histone deacetylases, Hda1 and Rpd3 (hdac∆), Adr1 is bound to its target promoters recruiting what appears to be an inactive RNA ploymerase II preinitiation complex (PIC). To determine whether Bmh activity inhibits this inactive PIC and the generality of this effect on glucose-repressed gene expression, the mRNA profiles of wild type, bmh mutant, hdac mutant, and bmh hdac mutant cells grown in high glucose medium were compared.

ORGANISM(S): Schizosaccharomyces pombe Saccharomyces cerevisiae

PROVIDER: GSE40116 | GEO | 2013/01/15

SECONDARY ACCESSION(S): PRJNA172859

REPOSITORIES: GEO

Similar Datasets

2013-01-15 | E-GEOD-40116 | biostudies-arrayexpress
2023-03-11 | PXD029840 | Pride
2019-02-27 | GSE122734 | GEO
2010-09-23 | E-GEOD-17521 | biostudies-arrayexpress
2012-03-01 | GSE27908 | GEO
2010-09-23 | GSE17521 | GEO
2023-03-11 | PXD033638 | Pride
2020-01-09 | GSE143305 | GEO
2017-03-15 | E-MTAB-2827 | biostudies-arrayexpress
2013-03-02 | E-GEOD-43539 | biostudies-arrayexpress