The galactose regulator GalX regulates the D-galactose oxido-reductive pathway in Aspergillus niger.

ABSTRACT: Galactose catabolism in Aspergillus nidulans is regulated by at least two regulators, GalR and GalX. In Aspergillus niger only GalX is present, and its role in D-galactose catabolism in this fungus was investigated. Phenotypic and gene expression analysis of a wild type and a galX disruptant revealed that GalX does not substitute for the absence of GalR in A. niger, it regulates the D-galactose oxido-reductive pathway, but not the Leloir pathway. Four genes, including the recently characterized ladB (galactitol dehydrogenase) were found to have differencial expressions that are highly relevant to GalX , indicating a novel oxido-reductive pathway in A.niger .

ORGANISM(S): Aspergillus niger Aspergillus niger CBS 513.88

PROVIDER: GSE40219 | GEO | 2012/09/20

SECONDARY ACCESSION(S): PRJNA173216

REPOSITORIES: GEO