Other,Multiomics

Dataset Information

1K

High-resolution transcriptome and genome-wide dynamics of RNA polymerase and NusA in Mycobacterium tuberculosis


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

INSTRUMENT(S): Illumina Genome Analyzer IIx (Mycobacterium tuberculosis)

SUBMITTER: Swapna Uplekar 

PROVIDER: GSE40862 | GEO | 2012-12-01

SECONDARY ACCESSION(S): PRJNA175136 GSE40845 GSE40846

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
GSE40862_RAW.tar Raw
filelist.txt Txt
Items per page:
1 - 2 of 2
altmetric image

Publications

High-resolution transcriptome and genome-wide dynamics of RNA polymerase and NusA in Mycobacterium tuberculosis.

Uplekar Swapna S   Rougemont Jacques J   Cole Stewart T ST   Sala Claudia C  

Nucleic acids research 20121207 2


To construct a regulatory map of the genome of the human pathogen, Mycobacterium tuberculosis, we applied two complementary high-resolution approaches: strand-specific RNA-seq, to survey the global transcriptome, and ChIP-seq, to monitor the genome-wide dynamics of RNA polymerase (RNAP) and the anti-terminator NusA. Although NusA does not bind directly to DNA, but rather to RNAP and/or to the nascent transcript, we demonstrate that NusA interacts with RNAP ubiquitously throughout the chromosome,  ...[more]

Similar Datasets

| S-EPMC3553938 | BioStudies
| E-GEOD-40845 | BioStudies
| E-GEOD-40846 | BioStudies
2012-12-01 | E-GEOD-40846 | ArrayExpress
2012-12-01 | E-GEOD-40845 | ArrayExpress
| GSE40846 | GEO
| PRJNA175136 | ENA
| S-EPMC6958063 | BioStudies
| S-EPMC3898074 | BioStudies
| E-MTAB-1616 | BioStudies