Gonadal DNA methylomes of half-smooth tongue sole Cynoglossus semilaevis

ABSTRACT: Environmental sex determination (ESD) occurs in divergent, phylogenetically unrelated taxa, and in some species co-occurs with genetic sex determination (GSD) mechanisms. Although epigenetic regulation in response to environmental effects has long been proposed to be associated with ESD, a systemic analysis on epigenetic regulation of ESD is still lacking. Using half-smooth tongue sole (Cynoglossus semilaevis) as a model – a marine fish which has both ZW chromosomal GSD and temperature-dependent ESD – we investigated the role of DNA methylation in transition from GSD to ESD by comparing gonadal DNA methylomes of parental females, parental pseudo-males, F1 females, F1 pseudo-males and normal males.

ORGANISM(S): Cynoglossus semilaevis

PROVIDER: GSE41129 | GEO | 2014/01/23

SECONDARY ACCESSION(S): PRJNA175873

REPOSITORIES: GEO