Effect of glucose availability on microRNA expression and Ago2 occupancy.

ABSTRACT: For cells to grow and proliferate both a growth signal and available nutrients are required. Several lines of evidence suggest that there is recriprocal regulation of nutrients by growth signals and growth signals by nutrients. Since microRNAs are regulated by growth signals, we sought to determine if microRNAs could also be regulated by nutrient availability. We found that several microRNAs change expression following glucose starvation and that their Ago2 occupancy remains constant.

ORGANISM(S): Mus musculus

PROVIDER: GSE41921 | GEO | 2012/12/17

SECONDARY ACCESSION(S): PRJNA178569

REPOSITORIES: GEO