Polysomal, free mRNP, and total cellular mRNA of J774.1 before and after LPS stimulation

ABSTRACT: Bacterial lipopolysaccharide(LPS) dramatically activates macrophages. So far, dozen of papers indicated that many proinflammatory molecules are transcriptionaly regulated during response. Despite of this,translational regulation is not fully elucidated especially in a comprehensive fashion. In this series, we investigated expression profiles of translation active (polysome) inactive (free mRNP) mRNAs of a typical mouse macrophage cell line, J774.1. Moreover, we also measured total cellular RNA level as a reference. Keywords: time-course

ORGANISM(S): Mus musculus

PROVIDER: GSE4288 | GEO | 2008/02/05

SECONDARY ACCESSION(S): PRJNA94783

REPOSITORIES: GEO