An integrative genomic and transcriptomic analysis reveals potential targets associated with cell proliferation in Uterine Leiomyomas

ABSTRACT: Copy number alterations data and transcriptional profiling of uterine leiomyomas tumor samples for integrative analysis. Goal was to determine identify genomic gains and/or losses associated with up and/or down expressed genes, respectively. After, it was applied GSEA and CONEXIC algorithm to integrate the data. Protein-Protein interactions also was building and the data were validated using qRT-PCR and IHC techniques.

ORGANISM(S): Homo sapiens

PROVIDER: GSE43027 | GEO | 2012/12/20

SECONDARY ACCESSION(S): PRJNA184073

REPOSITORIES: GEO