Canonical Nlrp3 inflammasome activation links systemic age-related inflammation with functional decline

ABSTRACT: This experiment was performed to analyze the contribution of NLRP3 inflammasome activation to age-related changes in hippocampal RNA. The hypothesis was that decreased inflammasome activation would reduce hippocampal inflammation. Results indicate that inflammasome knockout animals are protected from age-related changes in hippocampal gene expression

ORGANISM(S): Mus musculus

PROVIDER: GSE43034 | GEO | 2013/09/05

SECONDARY ACCESSION(S): PRJNA184139

REPOSITORIES: GEO