A systems approach identifies progeroid Ercc1[-/Δ] mice as a model system for kidney aging.

ABSTRACT: Using these samples, it has been shown that the transcriptional landscape in glomeruli of Ercc1[-/Δ] mice at a rather young age of 14 weeks mimics that of mice which have undergone real-life renal aging. Thus, young Ercc1[-/Δ] mice can be used as a model system for glomerular aging in future studies.

ORGANISM(S): Mus musculus

PROVIDER: GSE43061 | GEO | 2012/12/21

SECONDARY ACCESSION(S): PRJNA184201

REPOSITORIES: GEO