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Gefitinib sensitivity in NSCLC cell lines

ABSTRACT: Eleven NSCLC cell lines with widely divergent gefitinib sensitivities were compared using gene expression. Genes associated with gefitinib response were used to classify additional NSCLC lines with unknown gefitnib sensitivity. A subset of the test set data was tested for gefitinib sensitivity, and results correlated strongly with the gene expression-based predictions All eleven training set lines, and seven test set lines had both HGU133A and B chips done, while other test set lines had only HGU133As. Keywords: cell response comparison

ORGANISM(S): Homo sapiens

PROVIDER: GSE4342 | GEO | 2006/08/31

SECONDARY ACCESSION(S): PRJNA94835

REPOSITORIES: GEO

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