Transcriptomics,Genomics

Dataset Information

43

Ampicillin treatment (100 ug/ml) in M9 + glucose, timecourse


ABSTRACT: Responses of Escherichia coli as they are treated to 100 ug/ml Ampicillin in M9 + glucose Keywords: time course Overall design: Escherichia coli cells sampled at several time points (5, 10, 20, 30, 40, 50 min) after addition of 100 ug/ml Ampicillin in M9 + glucose vs 0 min untreated

INSTRUMENT(S): Khodursky Lab E. coli B 4290 ORFs Microarray

SUBMITTER: Dipen Sangurdekar  

PROVIDER: GSE4357 | GEO | 2006-03-08

SECONDARY ACCESSION(S): PRJNA94807

REPOSITORIES: GEO

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Publications

A classification based framework for quantitative description of large-scale microarray data.

Sangurdekar Dipen P DP   Srienc Friedrich F   Khodursky Arkady B AB  

Genome biology 20060420 4


Genome-wide surveys of transcription depend on gene classifications for the purpose of data interpretation. We propose a new information-theoretical-based method to: assess significance of co-expression within any gene group; quantitatively describe condition-specific gene-class activity; and systematically evaluate conditions in terms of gene-class activity. We applied this technique to describe microarray data tracking Escherichia coli transcriptional responses to more than 30 chemical and phy  ...[more]

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