Transcriptomics

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Response to Neoadjuvant Chemotherapy in Triple Negative Breast tumors.


ABSTRACT: In a cohort study of 7 women with primary invasive breast cancer, we obtained a tumor specimen before (biopsy) and after (tumorectomy) 4 cycles of NAC with epirubicine and cyclophosphamide, followed by 4 cycles of taxanes. Total RNA was extracted from tumor specimens and the whole transcriptome was quantified with Affymetrix HuGene1.1ST. Molecular functions changing during chemotherapy were searched.

ORGANISM(S): Homo sapiens

PROVIDER: GSE43816 | GEO | 2016/03/24

SECONDARY ACCESSION(S): PRJNA187494

REPOSITORIES: GEO

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