Geometric control of the coronary artery endothelial cell transcriptome following serum starvation

ABSTRACT: Analysis of the effects of cell shape on human coronary artery endothelial cell transcription. The hypothesis is that defined alterations in endothelial cell shape uniquely affect the endothelial transcriptome. Human coronary artery endothelial cells were plated onto spatially defined micropatterns (Cytoo) forcing them to conform to Disc, Crossbow, H, Y, or L shapes. As a control, human coronary artery endothelial cells were plated on non-restrictive areas of the Cytoo growth plate. Cells were serum starved for 48 hours prior to mRNA collection.

ORGANISM(S): Homo sapiens

PROVIDER: GSE44167 | GEO | 2013/06/01

SECONDARY ACCESSION(S): PRJNA188937

REPOSITORIES: GEO