High resolution transcriptome-wide RNA cytosine methylome of Mouse Embryonic Fibroblasts

ABSTRACT: We report high resolution transcriptome-wide RNA cytosine methylome of Mouse Embryonic Fibroblasts (MEFs) revealed by an optimized new RNA bisulfite sequencing approach. Comparison of RNA methylation profile from wild-type and Dnmt2 -/- MEFs shows that only C38 in three tRNAs (tRNA-Asp, Gly and Val) is the target of Dnmt2 in MEFs at normal conditions.

ORGANISM(S): Mus musculus

PROVIDER: GSE44359 | GEO | 2013/04/21

SECONDARY ACCESSION(S): PRJNA189560

REPOSITORIES: GEO