Transcriptomics,Genomics

Dataset Information

49

Expression data from lupus NZB/W and NZW/BXSB mouse prenephritic kidneys


ABSTRACT: We defined the shared and unique features of systemic lupus erythematosus (SLE) nephritis in 2 mouse models of proliferative renal disease. We identified shared inflammatory mechanisms of SLE nephritis that can be therapeutically targeted. Some common mechanisms are shared with non-immune-mediated renal diseases, suggesting that new strategies to prevent tissue hypoxia and remodeling may be useful in SLE nephritis. Overall design: RNA from whole kidneys was extracted and processed for hybridization on Affymetrix microarrays.

INSTRUMENT(S): Affymetrix GeneChip Mouse Genome 430 2.0 Array [CDF: Mm_ENTREZG_10]

SUBMITTER: Celine C Berthier 

PROVIDER: GSE44691 | GEO | 2014-12-31

SECONDARY ACCESSION(S): PRJNA191007

REPOSITORIES: GEO

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