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Gene expression in post cardiac surgery acute kidney injury

ABSTRACT: To determine the changes in intra-renal gene expression in a novel large animal model of post Cardiopulmonary Bypass (CPB) acute kidney injury, we collected renal medulla samples obtained 24hours post intervention. The transcriptional profile of the mRNA in these samples was measured with gene array technology.

ORGANISM(S): Sus scrofa

PROVIDER: GSE44782 | GEO | 2014/09/29

SECONDARY ACCESSION(S): PRJNA191780

REPOSITORIES: GEO

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Gene expression in post cardiac surgery acute kidney injury

Project description:To determine the changes in intra-renal gene expression in a novel large animal model of post Cardiopulmonary Bypass (CPB) acute kidney injury, we collected renal medulla samples obtained 24hours post intervention. The transcriptional profile of the mRNA in these samples was measured with gene array technology. Pigs were subjected to 2.5 hours of general anaesthesia or 2.5 hours of CPB under general anaesthesia. Renal medulla samples were collected 24 hours post intervention.

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