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Affymetrix expression data from colon cancer patient tissues

ABSTRACT: Gene expression profiling of 111 colon tissues from tumors and adjacent noncancerous tissues. Genotypes for the rs5995355 in NCF4 are included to identify genes whose expression are associated with this genotype.

ORGANISM(S): Homo sapiens

PROVIDER: GSE44861 | GEO | 2014/02/19

SECONDARY ACCESSION(S): PRJNA192427

REPOSITORIES: GEO

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Affymetrix expression data from colon cancer patient tissues

Project description:Gene expression profiling of 111 colon tissues from tumors and adjacent noncancerous tissues. Genotypes for the rs5995355 in NCF4 are included to identify genes whose expression are associated with this genotype. RNA from fresh frozen colon tissues were extracted using Trizol and hybridized to Affymetrix U113A arrays

2014-02-19 | E-GEOD-44861 | biostudies-arrayexpress

Copy number variation profiling of gastric tissues: Cancer Samples vs. Matched Adjacent Noncancerous Samples

Project description:Copy number variation profiling of gastric tissues comparing gastric cancer tissues with matched adjacent noncancerous tissues. Goal was to determine the effects of chromosomal imbalances on gene expression and carcinogenesis or progression. 27 pairs of gastric tissues: gastric cancer tissues vs. matched adjacent noncancerous tissues.

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LncRNA expression profile in gastric cancer specimens and adjacent noncancerous tissues

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Copy number variation profiling of gastric tissues: Cancer Samples vs. Matched Adjacent Noncancerous Samples

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Expression data from gastric tissues: Cancer Samples vs. Matched Adjacent Noncancerous Samples

Project description:To elucidate gene expression associated with copy number changes, we performed a genome-wide copy number and expression microarray analysis of 25 pairs of gastric tissues. 25 pairs of gastric tissues: gastric cancer tissues vs. matched adjacent noncancerous tissues.

2012-05-22 | E-GEOD-33335 | biostudies-arrayexpress

Expression data from bladder tumors and adjacent normal tissues

Project description:miRNAs are involved in cancer development and progression,acting as tumor suppressors or oncogenes. Half of the human miRNAs are located in cancer-associated genomic regions and can function as tumor suppressor genes or oncogenes depending on their targets miRNA profiling was performed on paired bladder cancer tissues and differentially expressed miRNAs were identified in BC and adjacent noncancerous tissues of any disease stage/grade.

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Cancer Samples vs. Matched Adjacent Noncancerous Samples

Project description:This SuperSeries is composed of the following subset Series: GSE33335: Expression data from gastric tissues: Cancer Samples vs. Matched Adjacent Noncancerous Samples GSE33428: Copy number variation profiling of gastric tissues: Cancer Samples vs. Matched Adjacent Noncancerous Samples Refer to individual Series

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Gene expression profiling of tumor-adjacent histologically normal lung tissues from lung SCC patients

Project description:Tumor-adjacent noncancerous tissues often exhibited abnormalities on molecular levels, which is described as field effect of cancerization. Accumulated evidence demonstrated that filed effect may also play important role in cancer progression. In the present study, we found that the gene expression profile in noncancerous lung tissues adjacent to lung squamous cell carcinoma (SCC) was significantly associated with regional lymph node status of patients. Significance Analysis of Microarrays (SAM) showed that 121 genes were significantly associated with lymph node metastasis (delta=0.75, FDR=0.069). Interestingly, all of the significant genes were up-regulated in the lymph node positive samples. For these genes, the most significant biological GO terms were extracellular structure organization, cell adhesion, regulation of cell motion/migration, and vessel development, etc, which were also involved in EMT process supported by another experiment in vitro. Tumor-adjacent histologically normal lung tissues were collected from 60 primary lung SCC patients, of whom 34 (56.7%) suffered regional lymph node metastasis. Gene expression profiling analysis of these samples was performed using Agilent 4x44K human whole genome gene expression microarray (G4112F).

2014-10-06 | E-GEOD-40588 | biostudies-arrayexpress

Gene expression profiling of tumor-adjacent histologically normal lung tissues from lung SCC patients

2014-10-06 | GSE40588 | GEO

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