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Genome-wide methylation and expression analysis of two breast cancer cell lines [RNA-Seq]

ABSTRACT: To improve our understanding of the relationships between methylation and expression we profiled mRNA expression and single-base resolution methylation levels for two breast cancer cell lines, MCF7 and T47D. Expression was profiled using RNA-seq. Methylation was assayed using Methyl-MAPS, which uses methylation-sensitive and -dependent restriction enzyme digests followed by high-throughput sequencing to identify methylation levels at individual CpGs (Edwards et al. 2010, Genome Research).

ORGANISM(S): Homo sapiens

PROVIDER: GSE45335 | GEO | 2013/06/15

SECONDARY ACCESSION(S): PRJNA193492

REPOSITORIES: GEO

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Genome-wide methylation and expression analysis of two breast cancer cell lines [Methyl-MAPS]

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