Profiling of glycerol- and CTX-induced models of muscle regeneration in mice

ABSTRACT: Utilizing glycerol and cardiotoxin (CTX) injections in the tibialis anterior muscles of M. musculus provides models of skeletal muscle damages followed by skeletal muscle regeneration. In particular, glycerol-induced muscle regeneration is known to be associated with ectopic adipogenesis. We characterized genome-wide expression profiles of tibialis anterior muscles from wild-type mice injured by either glycerol or CTX injection. Our goal was to detect gene expression changes during the time course of glycerol-induced and CTX-induced muscle regeneration models, that can lead to ectopic adipocyte accumulation.

ORGANISM(S): Mus musculus

PROVIDER: GSE45577 | GEO | 2013/08/16

SECONDARY ACCESSION(S): PRJNA194615

REPOSITORIES: GEO