Transcriptomics

Dataset Information

0

Whole-genome expression profiling of melanoma progression.


ABSTRACT: To gain insights into the genetic profile of every stage of the melanoma progression pathway, and to determine to what extent these profiles are similar or distinct, we performed whole-genome expression profiling of tissue specimens representing normal skin, benign and atypical nevi, and early and advanced-stage melanomas. The results of this study provide first-time evidence that significant molecular changes occur distinctly at the border of/transition from melanoma in situ to primary melanoma, and that genes involved in mitotic cell cycle regulation and cell proliferation constitute the two leading categories of genes associated with these changes. Keywords: Stage comparative analysis

ORGANISM(S): Homo sapiens

PROVIDER: GSE4587 | GEO | 2006/04/01

SECONDARY ACCESSION(S): PRJNA94437

REPOSITORIES: GEO

Similar Datasets

2007-12-14 | E-GEOD-4587 | biostudies-arrayexpress
2024-01-28 | PXD044107 | Pride
2010-05-16 | E-GEOD-18509 | biostudies-arrayexpress
2018-07-19 | GSE112509 | GEO
2009-12-20 | GSE18510 | GEO
2009-12-20 | GSE18509 | GEO
2010-10-30 | E-GEOD-24996 | biostudies-arrayexpress
2024-05-15 | E-MTAB-14045 | biostudies-arrayexpress
2007-09-06 | E-GEOD-3189 | biostudies-arrayexpress
2010-05-07 | E-GEOD-21463 | biostudies-arrayexpress