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Expression analysis of prostate tissue on locus 8q24 part 1

ABSTRACT: Investigation on expression levels of normal tissue from prostate cancer patients on locus 8q24. The region chr8:127640000-129120000 is tiled with 60 nt probes at 10 nt interval (hg18)

ORGANISM(S): Homo sapiens

PROVIDER: GSE45920 | GEO | 2013/04/11

SECONDARY ACCESSION(S): PRJNA196686

REPOSITORIES: GEO

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Expression analysis of prostate tissue on locus 8q24 part 1

Project description:Investigation on expression levels of normal tissue from prostate cancer patients on locus 8q24. The region chr8:127640000-129120000 is tiled with 60 nt probes at 10 nt interval (hg18) 7 chip study, using 7 independent samples.

2013-04-11 | E-GEOD-45920 | biostudies-arrayexpress

Expression analysis of prostate tissue on locus 8q24 part 2

Project description:Investigation on expression levels of normal tissue from prostate cancer patients on locus 8q24. The region chr8:127640000-129120000 is tiled with isothermal probes (hg17)

2013-04-11 | GSE45922 | GEO

Expression analysis of prostate tissue on locus 8q24 part 2

Project description:Investigation on expression levels of normal tissue from prostate cancer patients on locus 8q24. The region chr8:127640000-129120000 is tiled with isothermal probes (hg17) 7 chip study, using 7 independent samples.

2013-04-11 | E-GEOD-45922 | biostudies-arrayexpress

Expression analysis of prostate tissue on locus 8q24 part 3

Project description:Investigation on expression levels of normal tissue from prostate cancer patients on locus 8q24.

2013-04-11 | GSE45925 | GEO

The 8q24 cleft lip susceptibility locus is a remote Myc enhancer required for normal face morphology

Project description:A 640kb non-coding interval at 8q24 has been associated with an increased risk of non-syndromic cleft lip and palate (CLP) in humans, but the genes and pathways involved in this genetic susceptibility have remained elusive. With a large series of rearrangements engineered over the syntenic mouse region, we showed that this interval contains very remote cis-acting enhancers that control c-myc expression in the developing face. Deletion of this interval led to mild alteration of facial morphologies in mice and, sporadically, to CLP. At a molecular level, we identified mis-expression of several downstream genes, highlighting a combined impact on cranio-facial developmental network and general metabolic capacity. This dual molecular etiology may account for the prominent role to the 8q24 region in human facial dysmorphologies.

2014-04-03 | GSE52974 | GEO

The 8q24 cleft lip susceptibility locus is a remote Myc enhancer required for normal face morphology

2014-04-03 | E-GEOD-52974 | biostudies-arrayexpress

Expression analysis of prostate tissue on locus 8q24 part 3

Project description:Investigation on expression levels of normal tissue from prostate cancer patients on locus 8q24. 3 chips with 3 arrays each study, using 3 pairs of normal vs. tumor tissue and 3 replicates of the same sample. Each chip contained one pair of normal vs. tumor and one copy of the repeated sample.

2013-04-11 | E-GEOD-45925 | biostudies-arrayexpress

Sulfolobus solfataricus P2 growth curve, tiling arrays

Project description:Experimentally mapped transcriptome structure of Sulfolobus solfataricus P2 by hybridizing total RNA (including RNA species <200 nt) to genome-wide high-density tiling arrays (60 mer probes tiled every 25 nt).

2011-06-27 | GSE26779 | GEO

Methanococcus maripaludis S2 growth curve, tiling arrays

Project description:Experimentally mapped transcriptome structure of Methanococcus maripaludis S2 by hybridizing total RNA (including RNA species <200 nt) to genome-wide high-density tiling arrays (60 mer probes tiled every 14 nt).

2011-06-27 | GSE26777 | GEO

Time series of Escherichia coli BL21(DE3) growth curve, tiling arrays

Project description:Experimentally mapped transcriptome structure of Escherichia coli BL21(DE3) by hybridizing total RNA (including RNA species <200 nt) to genome-wide high-density tiling arrays (60 mer probes tiled every 10 nt).

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