Genome-wide search for exonic variants affecting translational efficiency

ABSTRACT: To date, the search for expression quantitative trait loci (eQTL) has centered entirely on transcription; variants with effects on mRNA translation have not been systematically studied. We tested the use of ribosomal association as proxy for translational efficiency of polymorphic mRNAs to develop a novel high throughput approach for translational cis-regulation in the human genome.

ORGANISM(S): Homo sapiens

PROVIDER: GSE46195 | GEO | 2013/04/18

SECONDARY ACCESSION(S): PRJNA198016

REPOSITORIES: GEO