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Identification of miRNAs regulated by TGF-b in human CD8+ T cells (small RNA-seq)

ABSTRACT: The goal of the current study was to identify miRNAs regulated by TGF-b in human CD8+ T cells and analyze the function of these miRNAs in shaping the immunomodulatory effect of TGF-b in these cells. We identified the miR-23a cluster to be upregulated and found that this cluster could target key molecules (IFN-g and LAMP1) involved in immune response by CD8+ T cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE46322 | GEO | 2014/08/01

SECONDARY ACCESSION(S): PRJNA198733

REPOSITORIES: GEO

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Identification of miRNAs regulated by TGF-b in human CD8+ T cells (expression)

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