Transcriptomics,Genomics

Dataset Information

33

ISR target genes in muscle of hSA::Fv2E-PERK


ABSTRACT: To identify the target genes of integrated stress reponse (ISR) in skeletal muscle, we have employed whole genome microarray expression in muscle specific Fv2E-PERK transgenic mice and C2C12 myotubes expressed in Fv2E-PERK. As a result, we identified that Fgf21 mRNA expression was commonly induced in skeletal muscle and C2C12. Overall design: The hSA::Fv2E-PERK transgenic mice were injected by AP20187 or mock. C2C12-Fv2E-PERK was also stimulated with AP20187.

INSTRUMENT(S): Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Probe Name version)

SUBMITTER: Seiichi Oyadomari  

PROVIDER: GSE46548 | GEO | 2015-12-26

SECONDARY ACCESSION(S): PRJNA200954

REPOSITORIES: GEO

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