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Transcriptional profiles of wild-type NCTC11168 and Cj0480c mutant grown without fucose

ABSTRACT: Strain specific growth of C. jejuni on fucose has been linked to a plasticity region of the chromosome (PR2) and confers a competitive advantage during intestinal colonization. Growth on fucose induces gene expression of PR2 genes, but the regulatory mechanism of the structural genes involved with fucose utilization is unknown. A mutant was constructed to examine the role of Cj0480c, a putative IclR-type transcriptional regulator, on PR2 gene expression. Transcriptional profiles of wild-type C. jejuni and the Cj0480c mutant strain grown without fucose may provide insight in to the extent of the fucose regulon and genes that are necessary for fucose utilization.

ORGANISM(S): Campylobacter jejuni

PROVIDER: GSE46808 | GEO | 2014/01/01

SECONDARY ACCESSION(S): PRJNA202440

REPOSITORIES: GEO

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Transcriptional profiles of NCTC11168 grown with or without 25mM fucose

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Transcriptional profiles of wild-type NCTC11168 and Cj0480c mutant grown without fucose

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Project description:Campylobacter jejuni Utilization of Fucose

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Project description:Competitive hybridization of V1 variant versus V26 variant of genome sequenced C. jejuni strain 11168 Keywords: repeat sample

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