Expression of miR-196a in Huntington's disease transgenic (HD) mice

ABSTRACT: We intend to screen altered genes after overexpression of miR-196a in HD transgenic mice. Two transgenic mouse lines were used in this study, including HD transgenic mice and HD transgenic mice overexpressing miR-196a. The mice were all at approximate 12 months of age. At this point, HD transgenic mice showed severve motor dysfunctions, whereas HD transgenic mice overexpressing miR-196a displayed mild motor dysfunctions.

ORGANISM(S): Mus musculus

PROVIDER: GSE47500 | GEO | 2013/05/30

SECONDARY ACCESSION(S): PRJNA205896

REPOSITORIES: GEO