Genomics

Dataset Information

19

Toxic effects of dietary TCDD on juvenile zebrafish


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

INSTRUMENT(S): NimbleGen Zebrafish 12x135K Array [090818_Zv7_EXPR]

SUBMITTER: Qing Liu  

PROVIDER: GSE47549 | GEO | 2014-12-01

SECONDARY ACCESSION(S): GSE47547 GSE47434PRJNA206051

REPOSITORIES: GEO

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Publications

Histopathologic alterations associated with global gene expression due to chronic dietary TCDD exposure in juvenile zebrafish.

Liu Qing Q   Spitsbergen Jan M JM   Cariou Ronan R   Huang Chun-Yuan CY   Jiang Nan N   Goetz Giles G   Hutz Reinhold J RJ   Tonellato Peter J PJ   Carvan Michael J MJ  

PloS one 20140702 7


The goal of this project was to investigate the effects and possible developmental disease implication of chronic dietary TCDD exposure on global gene expression anchored to histopathologic analysis in juvenile zebrafish by functional genomic, histopathologic and analytic chemistry methods. Specifically, juvenile zebrafish were fed Biodiet starter with TCDD added at 0, 0.1, 1, 10 and 100 ppb, and fish were sampled following 0, 7, 14, 28 and 42 d after initiation of the exposure. TCDD accumulated  ...[more]

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