Regulation of Mouse Lens Development and Gene Expression by Krüppel-Like Factor 4

ABSTRACT: Conditional disruption of Klf4 in the ectoderm-derived tissues of the eye results in defective cornea, conjunctiva and the lens. Expression of Klf4 is first detected in the embryonic day-12 (E12) mouse lens, peaks at E16, and declines thereafter. Lenses from Mice which were conditional null for Klf4 (Klf4CN) were characterized by morphology and transcriptome.

ORGANISM(S): Mus musculus

PROVIDER: GSE47694 | GEO | 2013/07/01

SECONDARY ACCESSION(S): PRJNA207302

REPOSITORIES: GEO