Genomics

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MicroRNA expression profiling of HepG2 liver cells after berberine chloride treatment


ABSTRACT: Berberine, an isoquinoline alkaloid isolated from many medicinal herbs such as Coptis chinensis, has a wide range of pharmacological effects including anti-cancer effects. Since xenobiotic drug-induced micoRNAs have recently emerged as key regulators in guiding their pharmacological effects and toxicity, we were interested in whether or not micoRNA expression was differentially altered by berberine treatment in HCC. Here, we used miRNA microarray to analyze microRNA expression profiles of HepG2 human hepatoma cell line after berberine chloride treatment or 0.08% DMSO as control.

ORGANISM(S): Homo sapiens

PROVIDER: GSE47821 | GEO | 2013/10/17

SECONDARY ACCESSION(S): PRJNA208015

REPOSITORIES: GEO

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