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Genes Differentially Expressed as a result of a fluconazole-resistant variant Candida albicans strain CaLY188 with trisomy of Chromosome R.

ABSTRACT: Transcriptional profiling of Candida albicans CaLY188 compared to the wild type SN152

ORGANISM(S): Candida albicans

PROVIDER: GSE48528 | GEO | 2014/06/24

SECONDARY ACCESSION(S): PRJNA210440

REPOSITORIES: GEO

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Genes Differentially Expressed as a result of a fluconazole-resistant variant Candida albicans strain CaLY188 with trisomy of Chromosome R.

Project description:Transcriptional profiling of Candida albicans CaLY188 compared to the wild type SN152 A fluconazole-resistant variant Candida albicans strain CaLY188 with trisomy of Chromosome R was selected to carry out the expression profile microarray. Two-condition experiment, CaLY188 vs.SN152. Biological replicates: 2 control, 2 transfected, independently grown and harvested. One replicate per array.

2014-06-24 | E-GEOD-48528 | biostudies-arrayexpress

Comparative genomics of a fluconazole-resistant variant Candida albicans strain CaLY188.

Project description:To investigate the diversity of gene contents of Candida albicans strain by array-based comparative genomic hybridization (array CGH; aCGH).

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Comparative genomics of a fluconazole-resistant variant Candida albicans strain CaLY188.

Project description:To investigate the diversity of gene contents of Candida albicans strain by array-based comparative genomic hybridization (array CGH; aCGH). A fluconazole-resistant variant Candida albicans strain CaLY188 was selected to carry out the comparative genomics microarray. Two-condition experiment, CaLY188 vs.SN152. Biological replicates: 2 control, 2 transfected, independently grown and harvested. One replicate per array.

2014-06-24 | E-GEOD-48529 | biostudies-arrayexpress

Comparative genomics of a fluconazole-resistant Candida albicans strain CaLY350.

Project description:To investigate the diversity of gene contents of Candida albicans strain by array-based comparative genomic hybridization (array CGH; aCGH).

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Comparative genomics of a fluconazole-resistant Candida albicans strain CaLY350.

Project description:To investigate the diversity of gene contents of Candida albicans strain by array-based comparative genomic hybridization (array CGH; aCGH). A fluconazole-resistant Candida albicans strain CaLY350 was selected to carry out the comparative genomics microarray. Two-condition experiment, CaLY350 vs.SN152. Biological replicates: 2 control, 2 transfected, independently grown and harvested. One replicate per array.

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Genes differentially expressed as a result of Candida albicans SC5314 exposure to pterostilbene

Project description:Transcriptional profiling of Candida albicans comparing pterostilbene treated cells with untreated cells

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Mistranslation accelerates the adaptation of Candida albicans to Fluconazole

Project description:The leucine CUG codon was reassigned to serine in the fungal pathogen Candida albicans. To clarify the biological role of this tuneable codon ambiguity on drug resistance, we evolved C. albicans strains that were engineered to mistranslate the CUG codon at constitutively elevated levels, in the presence and absence of the antifungal drug fluconazole. Elevated levels of mistranslation resulted in the rapid acquisition of resistance to fluconazole.

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Comparative genomics of the srd1 null mutant Candida albicans strain CaLY202.

Project description:To investigate the diversity of gene contents of Candida albicans strain by array-based comparative genomic hybridization (array CGH; aCGH).

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Whole genome sequencing of VMA11 deletion strain derived fluconazole adaptors in Candida albicans

Project description:Candida albicans strains SC5314 and YJB-T1891 were used as wild type to delete VMA11. The deletion strains (TJ926 and TJ927) were spread on YPD plate supplemented with 1μg/ml fluconazole. Randomly 96 adaptors derived from TJ926 and 96 adaptors derived from TJ927 were tested with disk diffusion assay. Among the resistant adaptors, randomly 15 adaptors (A4-A18) and 48 adaptors (A19-A66) derived from TJ926 were sequenced.

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Genes differentially expressed as a result of Candida albicans SC5314 exposure to pterostilbene

Project description:Transcriptional profiling of Candida albicans comparing pterostilbene treated cells with untreated cells Wild type Candida albicans strain SC5314 was selected to carry out the expression profile microarray. Two-condition experiment, pterostilbene treated vs. untreated cells. Biological replicates: 3 control, 3 pterostilbene treated, independently grown and harvested. One replicate per array.

2014-03-23 | E-GEOD-43690 | biostudies-arrayexpress

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