DNA unmethylome profiling by covalent capture of CpG sites

ABSTRACT: Here we present an approach for the mapping of unmethylated DNA. Our technique is based on DNA methyltransferase-directed transfer of activated groups (mTAG) and covalent biotin tagging of unmodified CpG sites followed by affinity enrichment and interogation on tiling microarrays or next generation sequencing.

ORGANISM(S): Homo sapiens

PROVIDER: GSE48994 | GEO | 2013/08/27

SECONDARY ACCESSION(S): PRJNA212537

REPOSITORIES: GEO