Transcriptomics

Dataset Information

41

Saturated fatty acids induced genes and ISR target genes in pancreatic beta cells


ABSTRACT: To identify the genes induced by lipotoxicity and integrated stress response in pancreatic beta cells, we have employed whole genome microarray expression in panvreatic beta cell line MIN6m9 cells. Overall design: First microarray analysis : Wild type MIN6m9 cells were treated with Palmitate, Oleate or negative control condition. Second microarray analysis : Wild type and Fv2E-PERK transgened MIN6m9 cells were treated with mock or artificial dimerizer AP20187(AP) in various time course.

INSTRUMENT(S): Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Probe Name version)

ORGANISM(S): Mus musculus  

SUBMITTER: Seiichi Oyadomari  

PROVIDER: GSE49647 | GEO |

SECONDARY ACCESSION(S): PRJNA214595

REPOSITORIES: GEO

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