Transcriptome analysis of Cox4-2 knockout mice after OVA challenge

ABSTRACT: Cytochrome c oxidase (COX) is a 13-subunit enzyme that is a key complex of the oxidative phosphorylation system of the mitochondria, which generates the vast majority of the energy of the cell.COX subunit IV is the largest nuclear-encode subunit with important regulatory functions concerning energy metabolism. COX4-2 has been knocked out. Our study indicated strong expression of Cox4-2 in lung and therefore we test this mutant line under OVA-challenge conditions expecting a new asthma mouse model.

ORGANISM(S): Mus musculus

PROVIDER: GSE49694 | GEO | 2015/07/15

SECONDARY ACCESSION(S): PRJNA214789

REPOSITORIES: GEO